The Grier Lab
Welcome to the home of the Grier Lab at the University of South Carolina School of Medicine Greenville!
Host-Pathogen Interactions and Intracellular Immunity
Our lab is interested in the intrinsic intracellular immune response to pathogens. We are primarily interested in responses to respiratory viral infections, such as influenza, RSV, or SARS-CoV-2, as well as secondary bacterial infections. Many of our bacterial studies are focused on the pathogen Acinetobacter baumannii, which is rapidly becoming resistant to most, if not all, approved classes of antibiotics.
Collaborative projects also include investigation of the impacts of socioeconomic factors on community-acquired pediatric infections to identify and address health disparities, as well as investigations into the interactions between stress, burnout, and immunity.
Our team is made up of a great group of undergraduate and medical student researchers. Check out the members of the lab on our Researchers page!
An important emphasis of the lab is student training. To help students starting out in any lab, we've put together a list of publicly available training information on common lab techniques, which you can find by heading over to the Training Resource Links .
Recent Publications and Preprints
The Multisystem Effects of Long COVID Syndrome and Potential Benefits of Massage Therapy in Long COVID Care
Elias Wheibe, Benjamin H. Dalkin, Haley C. Meltzer, Rebecca Russ-Sellers, and Jennifer T. Grier
International Journal of Therapeutic Massage and Bodywork
Severe Acute Respiratory Syndrome Coronavirus 2—Reactive Salivary Antibody Detection in South Carolina Emergency Healthcare Workers: September 2019—March 2020
Haley C. Meltzer, Jane L. Goodwin, Lauren A. Fowler, Thomas Britt, Ronald Pirrallo, and Jennifer T. Grier
MedRxiv
Acinetobacter baumannii infections that are resistant to treatment: warning signs from the COVID-19 pandemic
Ryan Ellis, Elena Roberts, Jennifer T. Grier and Steven E. Fiester
Future Microbiology
Immunomodulatory Regulation by Heat-Labile Enterotoxins and Potential Therapeutic Applications
Mary-Peyton A. Knapp, Taylor A. Johnson, Madison K. Ritter, Robert O. Rainer, Steven E. Fiester, Jennifer T. Grier, Terry D. Connell, and Sergio Arce
Expert Review of Vaccines
Community-Acquired, Extended-Spectrum β-Lactamase-Producing and Extensively Drug-Resistant Escherichia coli in a 28-Year-Old Pyelonephritis Patient Lacking Risk Factors
Connor W. Evins, Caroline M. Sutton, Sarah T. Withers, Jennifer T. Grier, Christine M. G. Schammel, and Steven E. Fiester
Antibiotics
Special Issue: Dissemination, Evolution, Molecular Mechanism of Antibiotic Resistance and Novel Approaches to Combat Multidrug Resistant Isolates
Two Acinetobacter baumannii Isolates Obtained from a Fatal Necrotizing Fasciitis Infection Display Distinct Genomic and Phenotypic Characteristics in Comparison to Type Strains
Jennifer T. Grier, Brock A. Arivett, Maria S. Ramírez, Renee J. Chosed, Jessica A. Bigner, Emily J. Ohneck, Maeva L. Metz, Cecily R. Wood, Sergio Arce, Andrea Tartaro, Ryan F. Relich, Luis A. Actis, and Steven E. Fiester
Frontiers in Cellular and Infection Microbiology
University of South Carolina School of Medicine Greenville
We prepare physicians committed to improving the health and wellness of your family and your community through creative teaching, innovative research, and quality clinical care.
USCSOMG is located in the up-and-coming city of Greenville, South Carolina. More information about USCSOMG can be found on the school's website.
If you have any questions, please contact Dr. Jennifer Grier.